- Evaluation of Plastic-Compressed Collagen for Conjunctival Repair in a Rabbit Model.
Evaluation of Plastic-Compressed Collagen for Conjunctival Repair in a Rabbit Model.
Tissue engineering. Part A (2018-12-07)
Joana Witt, Maria Borrelli, Sonja Mertsch, Gerd Geerling, Kristina Spaniol, Stefan Schrader
PMID30501562
摘要
Conjunctival integrity is crucial for a healthy ocular surface and visual acuity. In severe cases of inflammatory surface disorders or after trauma, thermal or chemical burns as well as after ocular surgery, a surgical reconstruction using conjunctival substitutes is required. Due to limitations of currently used substitutes, such as the amniotic membrane, there is a need for the development of new scaffolds of consistent quality for conjunctival reconstruction. This study explored the biocompatibility and surgical usability of plastic-compressed collagen as an alternative conjunctival substitute in a rabbit model.