CN
- A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin.
A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin.
Bioorganic & medicinal chemistry letters (2005-07-26)
Eleonora Rizzi, Sabrina Dallavalle, Lucio Merlini, Giovanni Luca Beretta, Graziella Pratesi, Franco Zunino
PMID16040242
摘要
A new synthesis of isoaurones related to the alleged structure of isoaurostatin, via Heck intramolecular cyclization of cinnamic esters of 2-iodophenols, is reported. The cytotoxic activity of these isoaurones is lower than that of the structurally very similar 4-arylcoumarins.
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