Valosin: isolation and characterization of a novel peptide from porcine intestine.

Valosin: isolation and characterization of a novel peptide from porcine intestine.

FEBS letters (1985-10-28)

W E Schmidt, V Mutt, M Carlquist, H Kratzin, J M Conlon, W Creutzfeldt

摘要

The isolation and primary structure of a novel gastrointestinal peptide, designated valosin, is described. The peptide was purified from porcine upper gut extracts using an HPLC and N-terminal sequence screening strategy which depends on chromatographic and structural characteristics as isolation criterion. The amino acid sequence of this peptide consists of 25 amino acid residues: