- Characterisation of CMP-sialic acid transporter substrate recognition.
Characterisation of CMP-sialic acid transporter substrate recognition.
Chembiochem : a European journal of chemical biology (2013-09-10)
Andrea Maggioni, Mark von Itzstein, Ingrid Bibiana Rodríguez Guzmán, Angel Ashikov, Alexandre S Stephens, Thomas Haselhorst, Joe Tiralongo
PMID24014346
摘要
CMP-sialic acid transporter: We report an in-depth, multidisciplinary, structural study that has identified the amino acid residues intimately involved in CMP-sialic acid transporter (CST) substrate specificity. Our data provide a significant contribution towards a better understanding the structure-function relationship of this important family of transporters and the rational design of CST inhibitors.
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