Synthesis of some 2-methylthiouracil nucleosides and its 5-halo analogues of 2-acetamido-2-deoxy-D-glucose.

This paper describes the regiospecific synthesis of 5-halo-2-methylthiouracil nucleosides by direct glycosylation followed by halogenation by an electrophilic halogen reagent and sodium azide under mild conditions. The compounds were suggested to be effective as antiviral agents.