[Antihypoxant activity in a series of 2-aminothiazole homologs].

The antihypoxic activity of a series of 2-aminothiazole homologs and the related N-syccinamic acids was studied on four hypoxia models. All 2-aminothiazoles possess antihypoxant properties, which increase with the complexity of the molecular structure. The attachment of a succinic acid fragment at the amino group reduced toxicity, but also decreased the antihypoxant activity of drugs.