In vivo effect of casticin on acute inflammation.

To investigate the anti-inflammatory effect of casticin of Fructus Viticis. Observations were made on the anti-inflammatory effect of casticin in the models of acute inflammation in vivo. Casticin inhibited significantly xylene-induced mouse ear edema, egg albumen-induced rat paw edema and acetic acid-induced mouse vascular permeability. Casticin has significant anti-inflammatory effect on acute inflammation, which is probably related to the inhibition of the inflammation factors. Casticin is the effective constituent contributing to the anti-inflammatory effect of Fructus Viticis.