Nucleophilic heterocyclic carbene as a novel catalyst for cyclopropanation of cyano acrylates.

Nucleophilic heterocyclic carbene as a novel catalyst for cyclopropanation of cyano acrylates.

Organic & biomolecular chemistry (2010-02-06)

Anabha E Raveendran, Rony Rajan Paul, Eringathodi Suresh, Vijay Nair

PMID20135050

摘要

Nucleophilic heterocyclic carbenes (NHCs) have been used for the first time as catalysts in the cyclopropanation of ethyl cyanocinnamates with phenacyl bromide by Michael-initiated ring-closure (MIRC).

材料

货号

品牌

产品描述

115835

Sigma-Aldrich

2-溴苯乙酮, 98%

77450

Supelco

2-溴苯乙酮, for GC derivatization, LiChropur^™, ≥99.0%