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  • Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide.

Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide.

Molecules (Basel, Switzerland) (2010-07-27)
Mark C Bagley, Christian Glover
摘要

Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.

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N-碘代琥珀酰亚胺, 95%