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  • Tandem reaction of propargylic alcohol, sulfonamide, and N-iodosuccinimide: synthesis of N-(2-iodoinden-1-yl)arenesulfonamide.

Tandem reaction of propargylic alcohol, sulfonamide, and N-iodosuccinimide: synthesis of N-(2-iodoinden-1-yl)arenesulfonamide.

Organic letters (2011-01-28)
Yuanxun Zhu, Guangwei Yin, Deng Hong, Ping Lu, Yanguang Wang
摘要

An efficient and straightforward strategy for the synthesis of N-(2-haloinden-1-yl)arenesulfonamides from propargylic alcohols and sulfonamides is described. Allenesulfonamide is postulated to be the key intermediate for this tandem transformation.

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Sigma-Aldrich
N-碘代琥珀酰亚胺, 95%