- Asymmetric pericyclic cascade approach to spirocyclic oxindoles.
Asymmetric pericyclic cascade approach to spirocyclic oxindoles.
Organic letters (2012-05-16)
Edward Richmond, Nicolas Duguet, Alexandra M Z Slawin, Tomáš Lébl, Andrew D Smith
PMID22583112
摘要
The reaction of chiral N-arylnitrones with carbocyclic alkylarylketenes generates spirocyclic oxindoles in good yields and with excellent levels of enantioselectivity (90-99% ee) via a pericyclic cascade process.
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