Merck
CN
  • Improved chemical stabilities for end-capped high performance liquid chromatography stationary phases based on poly(methyloctadecylsiloxane) thermally immobilized onto metalized silicas.

Improved chemical stabilities for end-capped high performance liquid chromatography stationary phases based on poly(methyloctadecylsiloxane) thermally immobilized onto metalized silicas.

Journal of chromatography. A (2012-09-12)
Carla G A da Silva, Carol H Collins
PMID22964048
摘要

Endcapped stationary phases were prepared after thermal immobilization of poly(methyloctadecylsiloxane) (PMODS) onto zirconized and titanized silica supports. These new stationary phases have lower densities of residual hydroxyl groups, according to infrared spectroscopy and 29Si CP-MAS NMR and as shown by the symmetrical peaks of basic compounds from the Tanaka, Engelhardt and SRM 870 test mixtures. Stability tests for the endcapped stationary phases, measured using severe alkaline conditions (70:30 (v/v) methanol:0.05 mol/L K2CO3/KHCO3, pH 10, 50 °C), revealed that the stabilities of these phases are greater than the stabilities of similar nonendcapped phases. The stationary phases showed good performance for the separation of basic pharmaceuticals.

材料
货号
品牌
产品描述
296848
Sigma-Aldrich
乙苯, anhydrous, 99.8%
03079
Supelco
乙苯, analytical standard
E12508
Sigma-Aldrich
乙苯, ReagentPlus®, 99%
487104
Supelco
乙苯溶液 溶液, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 5 mm × 8 in.
708046
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 10% in chloroform-d (99.8 atom % D)
40036
Supelco
乙苯溶液 溶液, certified reference material, 5000 μg/mL in methanol
717959
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 1% in chloroform-d (99.8 atom % D)
714917
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 5 mm × 8 in. , ultra-thin wall
736198
Supelco
乙苯溶液 溶液, NMR reference standard, 10% in chloroform-d (99.8 atom % D), NMR tube size 5 mm × 8 in. , ultra-thin wall
612065
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 10 mm × 8 in.
708054
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 0.1% in chloroform-d ("100%", 99.96 atom % D)
717967
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.1 %
551341
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 5% in chloroform-d (99.8 atom % D), TMS 2 %, NMR tube size 5 mm × 8 in.
710725
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 5% in chloroform-d (99.8 atom % D), TMS 1 %, NMR tube size 5 mm × 7 in.
487120
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 8 mm × 8 in.
733768
Sigma-Aldrich
乙苯溶液 溶液, NMR reference standard, 10% in chloroform-d (99.8 atom % D), NMR tube size 10 mm × 8 in.
612480
Supelco
乙苯溶液 溶液, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), chromium(III) acetylacetonate 0.1 mg/mL, TMS 0.01 %, NMR tube size 5 mm × 8 in.