Hybrid BaYbF(5) nanoparticles: novel binary contrast agent for high-resolution in vivo X-ray computed tomography angiography.

Hybrid BaYbF(5) nanoparticles: novel binary contrast agent for high-resolution in vivo X-ray computed tomography angiography.

Advanced healthcare materials (2012-11-28)

Yanlan Liu, Kelong Ai, Jianhua Liu, Qinghai Yuan, Yangyang He, Lehui Lu

摘要

A novel CT contrast agent denoted as BaYbF(5) @SiO(2) @PEG is presented. The as-prepared nanoparticles exhibit significantly enhanced contrast efficacy relative to clinical iodinated agents and maintain higher X-ray attenuation at different voltages, suitable for diagnostic imaging of various patients. Prolonged circulation time in vivo and low toxicity mean the nanoparticles perform excellently in in-vivo X-ray CT angiography.

材料

产品编号

品牌

产品描述

202746

Sigma-Aldrich

氟化钡, 99.99% trace metals basis

466069

Sigma-Aldrich

镱, powder, ≥99.9% trace rare earth metals basis

236101

Sigma-Aldrich

氟化钡, powder, 98%

432121

Sigma-Aldrich

氟化镱(III), anhydrous, powder, 99.98% trace metals basis

652458

Sigma-Aldrich

氟化钡, precipitated, 99.95% trace metals basis