Separation of the enantiomers of fluazifop and other 2-phenoxypropionic acids using chiral metal chelate additives in reversed-phase high-performance liquid chromatography.

Most of the work on the use of chiral ligand-exchange systems in reversed-phase liquid chromatography has been focussed on the resolution of the enantiomers of amino acids. This paper describes the novel use of L-prolyl-n-octylamide-Ni(II) in the mobile phase for the resolution of the enantiomers of fluazifop and other phenoxypropionic acids.