- Evaluation of bacterial growth inhibition by mercaptopropionic acid in metallo-β-lactamase detection on multidrug-resistant Acinetobacter baumannii.
Evaluation of bacterial growth inhibition by mercaptopropionic acid in metallo-β-lactamase detection on multidrug-resistant Acinetobacter baumannii.
Revista da Sociedade Brasileira de Medicina Tropical (2012-04-27)
Letícia Eichstaedt Mayer, Rosmari Hörner, Maisa Kräulich Tizotti, Rosiéli Martini, Magda Cristina Souza Marques Roehrs, Cláudia Barbisan Kempfer
PMID22535001
摘要
Metallo-β-lactamase (MBL) has been reported all over the world. The inhibitory effect of mercaptopropionic acid (MPA) on bacterial growth was evaluated by comparison between disk diffusion and broth dilution methodology with determination of the minimum inhibitory concentration (MIC) for multidrug-resistant Acinetobacter baumanni strains. MPA significantly inhibited growth of the strains. The use of MPA can affect the results in phenotypic methods of MBL detection.