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Merck
CN

N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase.

Bioorganic & medicinal chemistry letters (2001-03-30)
C Audouin, N Mestdagh, M A Lassoie, R Houssin, J P Hénichart
摘要

N-Aminoindoline derivatives were prepared and their 5-lipoxygenase inhibitory activities were evaluated in vitro and compared with those of phenidone and NDGA. Compound 4 presents the most effective 5-LO inhibition.

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1-苯基-3-吡唑烷酮, 97%