Synthesis of carbocyclic 2-substituted adenine nucleoside and related analogs.

Synthesis of carbocyclic 2-substituted adenine nucleoside and related analogs.

Nucleosides, nucleotides & nucleic acids (2008-09-13)

Fazila Zulfiqar, Hiroharu Kojima, Masayuki Nakanishi, Takayuki Ando, Yukio Kitade

摘要

2-Iodonoraristeromycin, 2-iodoaristeromycin and related analogs were synthesized to investigate their inhibitory activities against human and Plasmodium falciparum S-adenosyl-L-homocysteine hydrolases.