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Merck
CN
  • Short access to (+)-lupinine and (+)-epiquinamide via double hydroformylation.

Short access to (+)-lupinine and (+)-epiquinamide via double hydroformylation.

Organic letters (2009-12-30)
Etienne Airiau, Thomas Spangenberg, Nicolas Girard, Bernhard Breit, André Mann
摘要

Short and efficient access to (+)-lupinine and (+)-epiquinamide by means of an unprecedented double hydroformylation of a bis-homoallylic azide followed by a tandem catalytic hydrogenation/reductive bis-amination is reported.