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Merck
CN

Characterization of ethyl cellulose polymer.

Pharmaceutical development and technology (2011-08-25)
Tazin Mahnaj, Salah U Ahmed, Fotios M Plakogiannis
摘要

Ethyl cellulose (EC) polymer was characterized for its property before considering the interactions with the plasicizer. Ethocel Std.10 FP Premium from Dow chemical company USA was tested for its solubility, morphology and thermal properties. Seven percentage of EC solution in ethanol was found to be the right viscosity used to prepare the film. The EC polymer and EC film without any plasticizers showed almost identical thermal behavior, but in X-ray diffraction showed different arrangements of crystallites and amorphous region. Dynamic mechanical analysis of film showed that without a plasticizer, EC film was not flexible and had very low elongation with high applied force. The aim of the work was to avoid using the commercially available EC dispersions Surelease® and Aquacoat®; both already have additives on it. Instead, Ethocel EC polymer (powder) was characterized in our laboratory in order to find out the properties of polymer before considering the interactions of the polymer with various plasticizers.

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Sigma-Aldrich
乙基纤维素, 48.0-49.5% (w/w) ethoxyl basis
Sigma-Aldrich
乙基纤维素, 48.0-49.5% (w/w) ethoxyl basis
Sigma-Aldrich
乙基纤维素, viscosity 100 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl
Sigma-Aldrich
乙基纤维素, viscosity 46 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl
Sigma-Aldrich
乙基纤维素, viscosity 22 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl
Sigma-Aldrich
乙基纤维素, viscosity 300 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl
Sigma-Aldrich
乙基纤维素, viscosity 10 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl
Sigma-Aldrich
乙基纤维素, viscosity 4 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl