跳转至内容

CN

[Secondary osteoporosis or secondary contributors to bone loss in fracture. Bone metabolism and heavy metals (cadmium and iron) ].

[Secondary osteoporosis or secondary contributors to bone loss in fracture. Bone metabolism and heavy metals (cadmium and iron) ].

Clinical calcium (2013-09-04)

Shinsuke Kido

摘要

Fibroblast growth factor 23 (FGF23) is a bone-derived phosphaturic factor and is known to regulate blood inorganic phosphate (Pi) . Cadmium (Cd) , a toxic transition metal, which is widely used in industry, affecting human health and through occupational and environmental exposure. Phosphaturia has been documented following Cd exposure in both human and experimental animals. In animal study, Cd administration increases serum FGF23 concentrations. Moreover, medication such as infusion of select iron-containing compounds increases serum FGF23 concentrations, with patients developing hypophosphatemia. Thus, a relationship between metal ion (Cd and Fe) and FGF23 metabolic pathway has been proposed.

材料

产品编号

品牌

产品描述

Sigma-Aldrich

镉, granular, 30-80 mesh, ≥99%

Sigma-Aldrich

镉, powder, −100 mesh, 99.5% trace metals basis

Sigma-Aldrich

镉, granular, ≥99%, 5-20 mesh

Sigma-Aldrich

镉, shot, 3 mm, 99.999% trace metals basis

镉, foil, 100x100mm, thickness 1.0mm, as rolled, 99.99%

镉, foil, 10mm disks, thickness 1.0mm, as rolled, 100%

镉, rod, 100mm, diameter 40mm, 99.9%

镉, rod, 25mm, diameter 40mm, 99.9%

镉, rod, 100mm, diameter 10.0mm, 99.999%

镉, foil, 100x100mm, thickness 0.25mm, as rolled, 99.99+%

镉, foil, 2m coil, thickness 0.5mm, as rolled, 100%

镉, wire reel, 1m, diameter 1.2mm, as drawn, 99.99+%

镉, rod, 200mm, diameter 10.0mm, 99.999%

镉, foil, 25x25mm, thickness 0.5mm, as rolled, 99.999%

镉, foil, 50x50mm, thickness 0.25mm, as rolled, 99.9%

镉, foil, 150x150mm, thickness 0.5mm, as rolled, 99.99%

镉, foil, 30x50mm, thickness 0.5mm, as rolled, 99.999%

镉, foil, 50x50mm, thickness 0.125mm, as rolled, 99.99+%

镉, tube, 500mm, outside diameter 2.29mm, inside diameter 1.27mm, wall thickness 0.51mm, 99.95+%

镉, foil, 100x300mm, thickness 0.125mm, as rolled, 99.95%

镉, foil, 25x25mm, thickness 0.25mm, as rolled, 99.9%

镉, foil, 50x50mm, thickness 0.25mm, as rolled, 99.99+%

镉, foil, 50x50mm, thickness 2.0mm, as rolled, 99.99%

镉, foil, 4mm disks, thickness 0.5mm, as rolled, 99.95%

镉, foil, 8mm disks, thickness 0.005mm, 99.7+%

镉, foil, not light tested, 50x50mm, thickness 0.005mm, 99.7+%

镉, wire reel, 0.1m, diameter 1.2mm, as drawn, 99.99+%

镉, foil, 100x100mm, thickness 0.125mm, as rolled, 99.99+%

镉, foil, 150x150mm, thickness 0.25mm, as rolled, 99.95%

镉, foil, 25x25mm, thickness 0.125mm, as rolled, 99.99+%