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  • [Treatment of laryngeal granuloma with anti-extraesophageal reflux medication].

[Treatment of laryngeal granuloma with anti-extraesophageal reflux medication].

Acta otorrinolaringologica espanola (2003-12-16)
J P Benaixa, F Esteban, J M González-Pérez, R Martínez-Garrido
摘要

To asses the role of Gastroesophageal reflux in the genesis of laryngeal granulomas. Prospective series of 7 patients diagnosed of posterior laryngeal granuloma, 5 were male, and 2 female, ages ranging between 46 and 65 years, (only three with symptoms of gastroesophageal reflux), who followed an antireflux protocol (recommendations, omeprazol 20 mg, cisapride 20 mg, almagato 4000 mg daily). All cases did well, showing complete healing of the larynx 60 days after the beginning of treatment. Gastroesophageal reflux is an important factor in the genesis of posterior laryngeal granulomas. It seems appropriate to start an antireflux regimen before surgery, which can be chosen for non responders or cases with severe respiratory symptoms, hoarseness, or for definitive diagnosis.

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铝镁加, European Pharmacopoeia (EP) Reference Standard