CN

Molybdenum enzymes and molybdenum cofactor in mycobacteria.

Molybdenum enzymes and molybdenum cofactor in mycobacteria.

Journal of cellular biochemistry (2011-06-17)

Tingyu Shi, Jianping Xie

摘要

When intracelluar pathogens enter the host macrophages where in addition to oxidative and antibiotic mechanisms of antimicrobial activity, nutrients are deprived. Human pathogen Mycobacterium tuberculosis is one of macrophage parasitisms, which can replicate and persist for decades in dormancy state in virulent environments. It is very successful in escaping the killing mechanisms of macrophage. Molybdenum (Mo) enzymes involve in the global carbon, sulfur, and nitrogen cycles by catalyzing important redox reactions. There are several Mo enzymes in mycobacteria and they exert several important physiological functions, such as dormancy regulation, the metabolism of energy sources, and nitrogen source. Pterin-based Mo cofactor (Moco) is the common cofactor of the Mo enzymes in mycobacteria but the cofactor biosynthesis is nearly an untapped area. The present article discusses the physiological function of Mo enzymes and the structural feature of the genes coding for Moco biosynthesis enzymes in mycobacteria.

材料

货号

品牌

产品描述

Sigma-Aldrich

钼, powder, <150 μm, 99.9% trace metals basis

Sigma-Aldrich

钼, powder, 1-5 μm, ≥99.9% trace metals basis

Sigma-Aldrich

钼, foil, thickness 0.025 mm, ≥99.9% trace metals basis

Sigma-Aldrich

钼, powder, <150 μm, 99.99% trace metals basis

Sigma-Aldrich

钼, foil, thickness 0.1 mm, ≥99.9% trace metals basis

钼, foil, 15mm disks, thickness 0.005mm, 99.9%

Sigma-Aldrich

钼, wire, diam. 1.0 mm, 99.95% trace metals basis

Sigma-Aldrich

钼, nanopowder, <100 nm particle size (TEM), 99.8% trace metals basis

Sigma-Aldrich

钼, powder, 10 μm, ≥99.95% trace metals basis

钼, rod, 1000mm, diameter 3.0mm, centerless ground, 99.9%

Sigma-Aldrich

钼, foil, thickness 1.0 mm, ≥99.9% trace metals basis

钼, pellets, 100g, max. size 10mm, 99.9%

钼, rod, 1000mm, diameter 2.0mm, centerless ground, 99.9%

钼, rod, 50mm, diameter 5.0mm, 99.98%

钼, foil, light tested, 150x150mm, thickness 0.05mm, annealed, 99.9%

钼, foil, 1m coil, thickness 0.01mm, 99.9%

钼, foil, 150x150mm, thickness 0.5mm, annealed, 99.9%

钼, wire reel, 1000m, diameter 0.125mm, annealed, 99.95%

钼, pellets, 200g, max. size 10mm, 99.9%

钼, foil, 100x100mm, thickness 0.30mm, annealed, 99.9%

钼, rod, 1000mm, diameter 4.0mm, centerless ground, 99.9%

钼, mesh, 100x100mm, nominal aperture 0.44mm, wire diameter 0.07mm, 50 wires/inch, open area 67%, plain weave mesh

钼, wire, straight, 1000mm, diameter 0.25mm, 99.95%

钼, rod, 100mm, diameter 5.0mm, 99.98%

钼, wire reel, 10m, diameter 1.0mm, annealed, 99.95%

钼, foil, 150x150mm, thickness 0.25mm, annealed, 99.9%

钼, rod, 150mm, diameter 5.0mm, 99.98%

钼, pellets, 50g, max. size 10mm, 99.9%

钼, foil, 100x100mm, thickness 0.1mm, annealed, 99.9%

钼, foil, 100x100mm, thickness 0.20mm, annealed, 99.9%