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Merck
CN

Cobalt sensitization and dermatitis: considerations for the clinician.

Dermatitis : contact, atopic, occupational, drug (2012-09-27)
Jacob P Thyssen
摘要

This clinical review article presents clinical and scientific data on cobalt sensitization and dermatitis. It is concluded that cobalt despite being a strong sensitizer and a prevalent contact allergen to come up on patch testing should be regarded as a very complex metal to test with. Exposure data together with clinical data from metal workers heavily exposed to cobalt suggest that patch-test reactions are sometimes false positive and that patch testers should carefully evaluate their clinical relevance.

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钴, powder, 2 μm particle size, 99.8% trace metals basis
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钴, granular, 99.99% trace metals basis
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钴, Carbon coated magnetic, nanopowder, <50 nm particle size (TEM), ≥99%
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钴, pieces, 99.5% trace metals basis
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钴, wire, diam. 1.0 mm, 99.995% trace metals basis
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钴, foil, thickness 0.1 mm, 99.95% trace metals basis
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钴, foil, thickness 1.0 mm, 99.95% trace metals basis
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钴, foil, thickness 0.1 mm, ≥99.99%
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钴, rod, diam. 5.0 mm, 99.95% trace metals basis
钴, foil, light tested, 25x25mm, thickness 0.01mm, 99.9%
钴, foil, 4mm disks, thickness 0.05mm, annealed, 99.9%
钴, foil, 8mm disks, thickness 0.003mm, 99.9%
钴, foil, 6mm disks, thickness 0.01mm, 99.9%
钴, foil, 4mm disks, thickness 0.007mm, 99.9%
钴, foil, 8mm disks, thickness 0.01mm, 99.9%
钴, foil, 25x25mm, thickness 0.25mm, as rolled, 99.9%
钴, foil, light tested, 50x50mm, thickness 0.0125mm, 99.9%
钴, wire reel, 0.5m, diameter 0.05mm, hard, 99.9%
钴, foil, 25mm disks, thickness 0.125mm, annealed, 99.9%
钴, foil, 8mm disks, thickness 0.006mm, 99.9%
钴, foil, 4mm disks, thickness 0.025mm, 99.9%
钴, foil, 6mm disks, thickness 0.008mm, 99.9%
钴, foil, 8mm disks, thickness 0.125mm, as rolled, 99.99+%
钴, foil, 6mm disks, thickness 0.006mm, 99.9%
钴, foil, 6mm disks, thickness 0.25mm, as rolled, 99.9%
钴, foil, 8mm disks, thickness 0.004mm, 99.9%
钴, foil, 8mm disks, thickness 0.025mm, 99.9%
钴, foil, 8mm disks, thickness 0.25mm, as rolled, 99.9%
钴, foil, light tested, 25x25mm, thickness 0.009mm, 99.9%
钴, foil, light tested, 25x25mm, thickness 0.015mm, 99.9%