A scalable synthesis of the thromboxane receptor antagonist 3-{3-[2-(4-chlorobenzenesulfonamido) ethyl]-5-(4-fluorobenzyl) phenyl} propionic acid via a regioselective Heck cross-coupling strategy.

A scalable synthesis of the thromboxane receptor antagonist 3-{3-[2-(4-chlorobenzenesulfonamido) ethyl]-5-(4-fluorobenzyl) phenyl} propionic acid via a regioselective Heck cross-coupling strategy.

Organic Process Research & Development (1998)

Waite DC and Mason CP.