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Merck
CN
  • Molecular cloning of a murine type III sodium-dependent phosphate cotransporter (Pit-2) gene promoter.

Molecular cloning of a murine type III sodium-dependent phosphate cotransporter (Pit-2) gene promoter.

Biochimica et biophysica acta (2001-11-24)
L Bai, J F Collins, H Xu, L Xu, F K Ghishan
摘要

We report the novel cloning and preliminary characterization of a murine type III sodium-dependent phosphate cotransporter (Pit-2) gene promoter. Five promoter/luciferase reporter gene constructs, -1816/+61, -1620/+61, -1223/+61, -600/+61 and -225/+61, showed significant luciferase activity (6-14-fold over background) when transfected into human colon carcinoma (Caco-2) and opossum kidney (OKP) cells.