- miR-320a is an independent prognostic biomarker for invasive breast cancer.
miR-320a is an independent prognostic biomarker for invasive breast cancer.
Oncology letters (2014-08-15)
Haiping Yang, Juan Yu, Lei Wang, DI Ding, Lei Zhang, Chengyu Chu, Qi Chen, Zude Xu, Qiang Zou, Xiuping Liu
PMID25120655
摘要
Breast cancer is one of the most common malignancies worldwide and is the second leading cause of cancer-related mortality among females. miRNAs are a class of small noncoding RNAs that are aberrantly expressed in human cancers. Due to their small size and stability, miRNAs have the potential to be efficacious clinical targets. MicroRNA-320a (miR-320a) has been shown to be dysregulated in multiple malignancies. In the present study, the expression levels of miR-320a were investigated in 15 paraffin-embedded