- N-myristoyltransferase.
N-myristoyltransferase.
Molecular and cellular biochemistry (2000-03-16)
R V Rajala, R S Datla, T N Moyana, R Kakkar, S A Carlsen, R K Sharma
PMID10718634
摘要
Myristoylation refers to the co-translational addition of a myristoyl group to an amino-terminal glycine residue of a protein by an ubiquitously distributed enzyme myristoyl-CoA:protein N-myristoyltransferase (NMT, EC 2.3.1.97). This review describes the basic enzymology, molecular cloning and regulation of NMT activity in various pathophysiological processes such as colon cancer and diabetes.