- Catalytic enantioselective thioester aldol reactions that are compatible with protic functional groups.
Catalytic enantioselective thioester aldol reactions that are compatible with protic functional groups.
Journal of the American Chemical Society (2005-05-19)
Derek Magdziak, Gojko Lalic, Hong Myung Lee, Kevin C Fortner, Allen D Aloise, Matthew D Shair
PMID15898756
摘要
This communication reports highly enantioselective and diastereoselective methyl malonic acid half thioester (MeMAHT) aldol reactions that are compatible with protic functional groups and enolizable aldehydes, affording syn S-phenyl thiopropionates.
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