Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics.

Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics.

Scientific reports (2016-11-04)

Bartosz Szczesny, Michela Marcatti, John R Zatarain, Nadiya Druzhyna, John E Wiktorowicz, Péter Nagy, Mark R Hellmich, Csaba Szabo

摘要

Therapeutic manipulation of the gasotransmitter hydrogen sulfide (H

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Sigma-Aldrich

MISSION^® esiRNA, targeting human CBS

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MISSION^® esiRNA, targeting human CTH