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  • Bacterial Peptide Deformylase Inhibition of Tetrazole-Substituted Biaryl Acid Analogs: Synthesis, Biological Evaluations, and Molecular Docking Study.

Bacterial Peptide Deformylase Inhibition of Tetrazole-Substituted Biaryl Acid Analogs: Synthesis, Biological Evaluations, and Molecular Docking Study.

Archiv der Pharmazie (2016-11-20)
Firoz A Kalam Khan, Rajendra H Patil, Manjiri Patil, Rohidas Arote, Devanand B Shinde, Jaiprakash N Sangshetti
摘要

The synthesis and screening of tetrazole-substituted biaryl acid analogs 7a-l as bacterial peptide deformylase (PDF) enzyme inhibitors is reported. The compounds 7e (IC

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Sigma-Aldrich
1,3-亚丙基丙烯, 99%