Merck
CN

CHRM1

cholinergic receptor, muscarinic 1

别名:
HM1, M1, M1R
物种:
UniProtKB ID:
基因ID:
  • Human(1128) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
  • Mouse(12669) cholinergic receptor, muscarinic 1, CNS
  • Rat(25229) cholinergic receptor, muscarinic 1
  • domestic guinea pig(100728041) cholinergic receptor, muscarinic 1
  • domestic cat(493664) cholinergic receptor, muscarinic 1
  • domestic cat(101093801) cholinergic receptor, muscarinic 1
  • dog(483776) cholinergic receptor, muscarinic 1
  • sheep(101117029) cholinergic receptor, muscarinic 1
  • cow(281684) cholinergic receptor, muscarinic 1
  • Horse(100064117) cholinergic receptor, muscarinic 1
  • naked mole-rat(101702102) cholinergic receptor, muscarinic 1

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Small Molecule - Agonist

货号
说明
物种
乙酰基-β-氯化甲基胆碱, ≥98% (TLC), powder,
物种
human
氧化震颤素M, solid,
物种
human
卡巴胆碱, ≥98% (titration), crystalline,
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
爱普杷嗪 盐酸盐, ≥98% (HPLC), powder,
物种
human
盐酸比哌立登 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
Telenzepine dihydrochloride hydrate, solid, ≥98% (HPLC),
物种
human
奎宁环, 97%,
物种
rat
哌仑西平 二盐酸盐, ≥98% (TLC), powder,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-Muscarinic Acetylcholine Receptor m1 Antibody, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
immunohistochemistry
western blot
Anti-CHRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-CHRM1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
抗 毒蕈碱乙酰胆碱受体 (M 1 ) 兔抗, affinity isolated antibody, lyophilized powder,
物种反应性
mouse, rat
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
盐酸阿米替林 盐酸盐, ≥98% (TLC), powder,
物种
human
氯氮平标准液, ,
物种
human, rat
氟哌啶醇, powder,
物种
human, rat

Proteins

货号
说明
物种
Ready-to-Assay M1 Acetylcholine (Muscarinic) Family Receptor Frozen Cells, ,
物种
human
ChemiScreen Membrane Preparation Human Recombinant M1 Muscarinic Acetylcholine Receptor, Human M1 GPCR membrane prepation for Radioligand binding Assays.,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CHRM1,
物种
human