Merck
CN

HRH1

histamine receptor H1

别名:
H1-R, hisH1
物种:
UniProtKB ID:
基因ID:
  • Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15465) histamine receptor H1
  • Rat(24448) histamine receptor H 1
  • naked mole-rat(101715481) histamine receptor H1
  • domestic cat(101088314) histamine receptor H1
  • domestic guinea pig(100135539) histamine receptor H1
  • chicken(100858928) histamine receptor H1
  • domestic guinea pig(100730517) histamine receptor H1
  • cow(281231) histamine receptor H1
  • dog(403813) histamine receptor H1
  • Zebrafish(735302) histamine receptor H1
  • Horse(100034110) histamine receptor H1
  • sheep(101121717) histamine receptor H1

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Small Molecule - Agonist

货号
说明
物种
组胺 二盐酸盐, ≥99.0% (AT),
物种
human
组胺 二盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
组胺 二盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
组胺, analytical standard,
物种
human
组胺, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
盐酸西替利嗪, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
苯海拉明 盐酸盐, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
苯海拉明 盐酸盐, ≥98% (HPLC),
物种
human
西替利嗪 盐酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human
地氯雷他定, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human

Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-HRH1 antibody produced in mouse, clone 3D1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
proximity ligation assay
Anti-Histamine Receptor 1 Antibody, CT, Chemicon®, from rabbit,
物种反应性
bovine, mouse, rat
应用
ELISA
western blot

Small Molecule - Blocker

货号
说明
物种
桂利嗪, European Pharmacopoeia (EP) Reference Standard,
物种
human
桂利嗪, powder,
物种
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
酮替芬 富马酸盐, ,
物种
human
L-组氨醇 二盐酸盐, ≥98 (TLC),
物种
mouse, rat, human
D-组氨酸 单盐酸盐 一水合物, ≥98% (TLC),
物种
mouse, rat, human
氯雷他定, ≥98% (HPLC), powder,
物种
rat, human
组胺, ≥97.0%,
物种
human, rat

Small Molecule - Ligand

货号
说明
物种
氯雷他定, ≥98% (HPLC), powder,
物种
rat, human
桂利嗪, powder,
物种
human

Small Molecule - Metabolite

货号
说明
物种
1-甲基组胺 二盐酸盐, ≥98% (TLC), powder,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
2-(2-吡啶基)乙胺, 95%,
物种
human
氟哌啶醇, powder,
物种
human, rat
氯氮平标准液, ,
物种
human, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Hrh1,
物种
mouse
MISSION® esiRNA, targeting human HRH1,
物种
human