PCDHB12
protocadherin beta 12
Synonyms:
PCDH-BETA12
Species:
Human PCDHB12 (56124), Mouse Pcdhb12 (93883), Rat Pcdhb12 (25133), domestic cat PCDHB12 (101095465), Domestic Rabbit PCDHB12 (100350727), cow PCDHB12 (100848799)
UniProtKB ID:
Gene ID:
- Human(56124) Summary: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]
- Mouse(93883) protocadherin beta 12
- Rat(25133) protocadherin beta 12
- domestic cat(101095465) protocadherin beta 12
- Domestic Rabbit(100350727) protocadherin beta 12
- cow(100848799) protocadherin beta 12
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PCDHB12 antibody produced in mouse, clone 1D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
esiRNA
Product Number
Description
Species