CN
PTPRM
protein tyrosine phosphatase, receptor type, M
别名:
PTPRL1, R-PTP-MU, RPTPM, RPTPU, hR-PTPu
物种:
Human PTPRM (5797), Mouse Ptprm (19274), Rat Ptprm (29616), Horse PTPRM (100059664), chicken PTPRM (426242), Domestic Rabbit PTPRM (100356969), domestic cat PTPRM (101080832), dog PTPRM (480203), cow PTPRM (536092), sheep PTPRM (101102951) ...展开
UniProtKB ID:
基因ID:
- Human(5797) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Mouse(19274) protein tyrosine phosphatase, receptor type, M
- Rat(29616) protein tyrosine phosphatase, receptor type, M
- Horse(100059664) protein tyrosine phosphatase, receptor type, M
- chicken(426242) protein tyrosine phosphatase, receptor type, M
- Domestic Rabbit(100356969) protein tyrosine phosphatase, receptor type, M
- domestic cat(101080832) protein tyrosine phosphatase, receptor type, M
- dog(480203) protein tyrosine phosphatase, receptor type, M
- cow(536092) protein tyrosine phosphatase, receptor type, M
- sheep(101102951) protein tyrosine phosphatase, receptor type, M
- domestic guinea pig(100714550) protein tyrosine phosphatase, receptor type, M
- naked mole-rat(101707728) protein tyrosine phosphatase, receptor type, M
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Antibodies
货号
说明
物种反应性
应用
Anti-Protein Tyrosine Phosphatase µ Antibody, clone SBK15, ascites fluid, clone SBK15, Chemicon®,
物种反应性
bovine, canine, human, mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-PTPRM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Proteins
货号
说明
物种