RAB1089
Human TNF-alpha ELISA Kit (for Lysates)
for cell and tissue lysate samples
Synonym(s):
TNF-Alpha
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Product Name
Human TNF-alpha ELISA Kit (for Lysates), for cell and tissue lysate samples
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type tissue lysate
sample type cell lysate
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 30 pg/ml
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TNF(7124)
Application
Please refer to the attached Protocolfor details.
Human tumor necrosis factor-alpha (TNF-α) ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) to quantify TNF-α in supernates of human acute lung infection model (ALIM), human umbilical vein endothelial cells (HUVEC) and human microvascular endothelial cells (HMEC-1).
Human tumor necrosis factor-alpha (TNF-α) ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) to quantify TNF-α in supernates of human acute lung infection model (ALIM), human umbilical vein endothelial cells (HUVEC) and human microvascular endothelial cells (HMEC-1).
Biochem/physiol Actions
Tumor necrosis factor-α (TNF-α) is a key immunomodulator and proinflammatory cytokine. It is implicated in the immune pathogenesis of various autoimmune, inflammatory diseases and hepatitis B virus (HBV) infection. Mutation in the gene increases the risk of susceptibility to diffuse large B-cell lymphoma (DLBCL) and marginal zone lymphoma. In addition, polymorphism in the gene leads to obsessive-compulsive disorder (OCD) and osteoarthritis (OA).
General description
This ELISA kit shows no cross-reactivity with any of the cytokines tested: Human ANG, CD23, Eotaxin, GCSF, GM-CSF, GRO-alpha, GRO-beta, GRO-gamma, I-309, IFN-gamma, IL-1 alpha, IL-1 beta, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p40), IL-12 (p70), IL-15, IL-16, IP-10, MCP-1, MCP-2, MCP-3, MCP-4, MCSF, MIG, MIP-1 alpha, MIP-1 beta, NAP-2, PDGF, PF-4
Tumor necrosis factor-α (TNF-α) is encoded by the gene mapped to human chromosome 6p21.3, within the major histocompatibility complex (MHC) class III region. The encoded protein belongs to the TNF superfamily.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
低风险生物材料
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