Oligonucleotides are short DNA or RNA molecules that are used in genetic testing, research, and forensics. Custom oligos are synthesized using phosphoramidite chemistry. See some of the most frequently asked questions regarding our custom oligo synthesis service.

Custom Oligos Modifications

We offer over 200 custom DNA oligos modification for both DNA, RNA oligonucleotides and sequencing to probes for gene.

Custom Oligo Blanket Purchase Orders

We are pleased to offer a tracking system for your custom oligo Blanket Purchase Orders. Our tracking system provides easy management of expenditures against your Blanket Purchase Order (P.O.). Simply register your Blanket P.O. to take advantage of the FREE

Oligonucleotide Quality Assurance: Quality Management System Components

Key components of our QMS (quality management system) include: certificates of analysis; document control; change notification; vendor management; business agreements; and, corrective and preventive actions.

Mpox qPCR Products

We are committed to providing researchers and assay developers with the reagents and technical expertise to support of the mpox outbreak. Explore our offering of world-class qPCR and supporting reagents that are suitable for mpox research and assay development.

OligoEvaluator™ for T_m Calculation & Primer Analysis

We offer an easy-to-use Oligo Analyzer tool, OligoEvaluator™ that provides better primer dimer analysis values for PCR, and serves as an online oligonucleotide sequence calculator and Tm calculator.

OligoArchitect™ Consultative

For more complex and demanding applications, utilize our consultative service to ensure the success of your assay.

No Template Control Oligos (NTCO)

If laboratory handling error has been ruled out, contaminated primers and probes may be to blame for a signal from the qPCR no template control.

Oligonucleotide Label Licenses

Label licenses for our oligonucleotide products, including Black Hole Quencher®, BlackBerry® Quencher, and Locked Nucleic Acid (LNA®).

Custom siRNA Duplex Plates

Use our synthetic, small interfering RNA (siRNA) duplex plates to identify gene function, elucidate pathways, and screen for potential new drug targets.

Pure & Simple Primers

We have developed an advanced proprietary technology ultra-high base coupling efficiency during synthesis of your oligos. Combined with optimized cartridge purification to enrich your oligo for full-length product, and 100% quality control by mass spectrometry, you can be assured of

WellRED Oligos

WellRED oligos use cyanine-based fluorescent dyes with high extinction coefficients that absorb in the near-infrared region, thereby reducing background noise from biological materials, resulting in highly sensitive detection.

Fast siRNA

We can quickly synthesize and ship custom siRNA using your sequences.

Dual-Labeled Probes

Dual-Labeled Probes are the most common probe type for qPCR and are often referred to as hydrolysis probes.

Custom cGMP Oligos Coming in 2023

If you commercialize Molecular Diagnostics (MDx), develop Laboratory Developed Tests (LDTs), or conduct preclinical research on therapeutics, then your final kit, assay, or modality must have an extraordinary level of quality to comply with strict regulatory or study standards.

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