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Merck
CN

MOGS

mannosyl-oligosaccharide glucosidase

别名:
CDG2B, CWH41, DER7, GCS1
物种:
UniProtKB ID:
基因ID:
  • Human(7841) Summary: This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(57377) mannosyl-oligosaccharide glucosidase
  • Zebrafish(567913) mannosyl-oligosaccharide glucosidase
  • sheep(101118003) mannosyl-oligosaccharide glucosidase
  • Horse(100069105) mannosyl-oligosaccharide glucosidase
  • domestic cat(101086221) mannosyl-oligosaccharide glucosidase
  • cow(516155) mannosyl-oligosaccharide glucosidase
  • domestic guinea pig(100736016) mannosyl-oligosaccharide glucosidase
  • naked mole-rat(101699668) mannosyl-oligosaccharide glucosidase
  • dog(483104) mannosyl-oligosaccharide glucosidase
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