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Merck
CN

MYOM1

myomesin 1

别名:
SKELEMIN
物种:
UniProtKB ID:
基因ID:
  • Human(8736) Summary: The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(17929) myomesin 1
  • Rat(316740) myomesin 1
  • naked mole-rat(101696403) myomesin 1
  • domestic cat(101088193) myomesin 1
  • Horse(100062232) myomesin 1
  • domestic guinea pig(100721489) myomesin 1
  • sheep(101104877) myomesin 1
  • cow(538404) myomesin 1, 185kDa
  • Domestic Rabbit(100347154) myomesin 1, 185kDa
  • chicken(395805) myomesin 1, 185kDa
  • dog(480191) myomesin 1

Custom & Knockdown Gene Products

Antibodies

产品编号
说明
物种反应性
应用
Anti-MYOM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-MYOM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

esiRNA

产品编号
说明
物种
MISSION® esiRNA, targeting human MYOM1,
物种
human