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Merck
CN

H7379

血红蛋白 人

lyophilized powder

别名:

HB

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352202
eCl@ss:
42030116
NACRES:
NA.61
MDL number:
Form:
lyophilized powder
Biological source:
human
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biological source

human

form

lyophilized powder

technique(s)

enzyme immunoassay: suitable

impurities

HIV and hepatitis B antigen, tested negative

solubility

H2O: soluble 20 mg/mL

UniProt accession no.

Quality Level

storage temp.

2-8°C

General description

血红蛋白是红细胞的主要成分,也是红细胞呈现红色的原因。它在红细胞中的正常浓度为34%。由于它能够将氧从肺部输送到身体组织,促进二氧化碳的返回转运,因此血红蛋白是脊椎动物最重要的呼吸蛋白。

Application

血红蛋白被用于开发检测视黄醇结合蛋白的快速酶免疫分析法。它也被内皮源性舒张因子用于抑制人血小板反应性。

Biochem/physiol Actions

Fe2+/Fe3+平衡是血液氧合的生理指标。脱氧血红蛋白通过将亚硝酸盐还原为NO(一种血管舒张剂,可促进血液流向缺氧组织)来辅助反馈回路。
氧气转运蛋白,NO清除剂

Disclaimer

仅供研究使用。本品在法国的科研应用受到监管,包括用于进口和出口活动(法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2)。如《公共卫生法典》所述,购买者(即最终用户)需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。
由于天然血红蛋白在空气中容易氧化,因此这些制剂可能主要是高铁血红蛋白。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mieke Steenbeke et al.
Clinical chemistry and laboratory medicine, 58(10), 1759-1767 (2020-07-11)
Objectives In this study, the possibilities of Fourier-transformed infrared spectroscopy (FTIR) for analysis of urine sediments and for detection of bacteria causing urinary tract infections (UTIs) were investigated. Methods Dried urine specimens of control subjects and patients presenting with various
Chiao-Wang Sun et al.
Circulation, 139(23), 2654-2663 (2019-03-25)
Nitrosation of a conserved cysteine residue at position 93 in the hemoglobin β chain (β93C) to form S-nitroso (SNO) hemoglobin (Hb) is claimed to be essential for export of nitric oxide (NO) bioactivity by the red blood cell (RBC) to
Rebeca M Torrente-Rodríguez et al.
PloS one, 12(4), e0175056-e0175056 (2017-04-05)
The first electrochemical immunosensor for the determination of fibroblast growth factor receptor 4 (FGFR4) biomarker is reported in this work. The biosensor involves a sandwich configuration with covalent immobilization of a specific capture antibody onto activated carboxylic-modified magnetic microcarriers (HOOC-MBs)
Nai-Jia Huang et al.
Nature communications, 8(1), 423-423 (2017-09-06)
A short half-life in the circulation limits the application of therapeutics such as single-domain antibodies (VHHs). We utilize red blood cells to prolong the circulatory half-life of VHHs. Here we present VHHs against botulinum neurotoxin A (BoNT/A) on the surface
Hsuan-Shun Huang et al.
The Journal of pathology, 240(4), 484-494 (2016-10-30)
Fallopian tube fimbrial epithelium is considered to be the major site of origin of ovarian high-grade serous carcinoma, with p53 loss being the earliest and universal change. We previously reported that reactive oxygen species (ROS) in the ovulatory follicular fluids

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