AAT Bioquest Cell Meter™ Generic Fluorimetric Caspase Binding Assay Kit

Our Cell Meter™ assay kits are a set of tools for monitoring cell viability. This particular kit is designed to monitor cell apoptosis through measuring generic caspases (caspase-1, -3, -4, -5, -6, -7, -8 and -9) activation in living cells. Caspases activation is widely accepted as a reliable indicator for cell apoptosis. Most caspases have substrate selectivity for the peptide sequence Val-Ala-Asp (VAD). This kit uses TF5-VAD-FMK as a fluorogenic indicator for most caspase activity. TF5-VAD-FMK is cell permeable, nontoxic, and irreversibly binds to activated casepase-1, -3, -4, -5, -6, -7, -8 and -9 in apoptotic cells.

Components:

• 500X Green-DCS1-1 vial (100 µL)
• 500X TF5-VAD-FMK-1 vial (100 µL)
• Assay Buffer-1 bottle (50 mL)

Cell Meter™ Generic Fluorimetric Caspase Binding Assay Kit *Red Fluorescence Optimized for Flow Cytometry* is manufactured by AAT Bioquest

Cell Meter™ is a trademark of AAT Bioquest