manufacturer/tradename
AAT Bioquest
General description
Mitochondrial autophagy (also called ”mitophagy”) appears to be involved in Alzheimer and Parkinson diseases, mainly induced by the accumulation of depolarized mitochondria. Cell Meter™ Mitochondrial Autophagy Mitophagy Iimaging Kit uses Mitophagy Red™ as the mitophagy probe, which enables the very rapid and uniform staining of mitochondria across a wide variety of mammalian cell types and translocate to lysosome upon induction of mitophagy. The Cell Meter™ Mitochondrial Autophagy Imaging Kit provides an excellent tool to be used as an indicator of mitophagy in suspended or attached live cells. The staining pattern of Mitophagy Red™in live cells is stable enough that it provides enough time for studying most live cell dynamic. The assay conditions are compatible with cell culture medium. The excitation/emission of the Mitophagy Red™ probe fits well the widely available Cy3/TRITC filter set and can easily be combined with GFP expressed cell lines if desired.
Components:
- Mitophagy Red™-1 vial
- Staining Buffer-1 bottle (50 mL)
- DMSO-1 vial (50 µL)
Cell Meter™ Mitochondrial Autophagy Imaging Kit *Red Fluorescence* is manufactured by AAT Bioquest
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