100439
碘化乙酰胆碱
98%
别名:
ACh
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关于此项目
线性分子式:
(CH3)3N(I)CH2CH2OCOCH3
化学文摘社编号:
分子量:
273.11
EC Number:
218-862-3
UNSPSC Code:
12352103
PubChem Substance ID:
Beilstein/REAXYS Number:
3571339
MDL number:
InChI key
SMBBQHHYSLHDHF-UHFFFAOYSA-M
InChI
1S/C7H16NO2.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
SMILES string
[I-].CC(=O)OCC[N+](C)(C)C
assay
98%
Gene Information
human ... CHRM3(1131)
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Biochem/physiol Actions
胆碱能突触中的内源性神经递质，通过增强肌膜动作电位来触发肌肉收缩反应。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Marie Briet et al.
Journal of the American Heart Association, 2(2), e000128-e000128 (2013-04-16)
Recent studies have raised concern about the safety of erythropoiesis-stimulating agents because of evidence of increased risk of hypertension and cardiovascular morbidity and mortality in chronic kidney disease (CKD) patients. In the present study, we investigated the effects of recombinant
Tracey Huynh et al.
Journal of medicinal chemistry, 56(20), 8196-8200 (2013-10-01)
The M4 mAChR is implicated in several CNS disorders and possesses an allosteric binding site for which ligands modulating the affinity and/or efficacy of ACh may be exploited for selective receptor targeting. We report the synthesis of a focused library
Xun Qian et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(1), 127-135 (2013-11-02)
Intermediate and small conductance KCa channels IK1 (KCa3.1) and SK3 (KCa2.3) are primary targets of endothelial Ca(2+) signals in the arterial vasculature, and their ablation results in increased arterial tone and hypertension. Activation of IK1 channels by local Ca(2+) transients
Saikat Ray et al.
Science (New York, N.Y.), 343(6173), 891-896 (2014-01-25)
Little is known about how microcircuits are organized in layer 2 of the medial entorhinal cortex. We visualized principal cell microcircuits and determined cellular theta-rhythmicity in freely moving rats. Non-dentate-projecting, calbindin-positive pyramidal cells bundled dendrites together and formed patches arranged
Yingchuan B Qi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(12), 5319-5325 (2013-03-22)
Excitatory acetylcholine motor neurons drive Caenorhabditis elegans locomotion. Coordinating the activation states of the backward-driving A and forward-driving B class motor neurons is critical for generating sinusoidal and directional locomotion. Here, we show by in vivo calcium imaging that expression
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