100439
碘化乙酰胆碱
98%
别名:
ACh
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关于此项目
线性分子式:
(CH3)3N(I)CH2CH2OCOCH3
化学文摘社编号:
分子量:
273.11
EC Number:
218-862-3
UNSPSC Code:
12352103
PubChem Substance ID:
Beilstein/REAXYS Number:
3571339
MDL number:
InChI key
SMBBQHHYSLHDHF-UHFFFAOYSA-M
InChI
1S/C7H16NO2.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
SMILES string
[I-].CC(=O)OCC[N+](C)(C)C
assay
98%
Gene Information
human ... CHRM3(1131)
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Biochem/physiol Actions
胆碱能突触中的内源性神经递质，通过增强肌膜动作电位来触发肌肉收缩反应。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Jeppe A Olsen et al.
The Journal of biological chemistry, 288(50), 35997-36006 (2013-10-31)
Positive allosteric modulators (PAMs) of α4β2 nicotinic acetylcholine receptors have the potential to improve cognitive function and alleviate pain. However, only a few selective PAMs of α4β2 receptors have been described limiting both pharmacological understanding and drug-discovery efforts. Here, we
Vincent Laurent et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(4), 1358-1369 (2014-01-24)
Decision-making depends on the ability to extract predictive information from the environment to guide future actions. Outcome-specific Pavlovian-instrumental transfer (PIT) provides an animal model of this process in which a stimulus predicting a particular outcome biases choice toward actions earning
Sulan Luo et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(4), 1842-1853 (2014-01-09)
This study was performed to discover and characterize the first potent α3β2-subtype-selective nicotinic acetylcholine receptor (nAChR) ligand. A novel α4/7-conotoxin, α-CTxLvIA, was cloned from Conus lividus. Its pharmacological profile at Xenopus laevis oocyte-expressed rat nAChR subtypes was determined by 2-electrode
Rosalyn J Moran et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(19), 8227-8236 (2013-05-10)
Acetylcholine (ACh) is a neuromodulatory transmitter implicated in perception and learning under uncertainty. This study combined computational simulations and pharmaco-electroencephalography in humans, to test a formulation of perceptual inference based upon the free energy principle. This formulation suggests that ACh
Marie Briet et al.
Journal of the American Heart Association, 2(2), e000128-e000128 (2013-04-16)
Recent studies have raised concern about the safety of erythropoiesis-stimulating agents because of evidence of increased risk of hypertension and cardiovascular morbidity and mortality in chronic kidney disease (CKD) patients. In the present study, we investigated the effects of recombinant
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