InChI
1S/CCl4/c2-1(3,4)5
InChI key
VZGDMQKNWNREIO-UHFFFAOYSA-N
SMILES string
ClC(Cl)(Cl)Cl
vapor density
5.32 (vs air)
vapor pressure
143 mmHg ( 30 °C), 91 mmHg ( 20 °C)
assay
99%
mp
−23 °C (lit.)
density
1.594 g/mL at 25 °C (lit.)
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 2 - Ozone 1 - Skin Sens. 1B - STOT RE 1 Inhalation
target_organs
Liver,Kidney
存储类别
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
J D Coombes et al.
Gut, 64(7), 1120-1131 (2014-06-07)
Chronic liver injury triggers a progenitor cell repair response, and liver fibrosis occurs when repair becomes deregulated. Previously, we reported that reactivation of the hedgehog pathway promotes fibrogenic liver repair. Osteopontin (OPN) is a hedgehog-target, and a cytokine that is
Kristina Søborg Pedersen et al.
Molecules (Basel, Switzerland), 25(5) (2020-03-07)
Despite promising anti-cancer properties in vitro, all titanium-based pharmaceuticals have failed in vivo. Likewise, no target-specific positron emission tomography (PET) tracer based on the radionuclide 45Ti has been developed, notwithstanding its excellent PET imaging properties. In this contribution, we present
Marc Mejias et al.
Gut, 64(4), 657-666 (2014-05-23)
Antiangiogenic strategies have been proposed as a promising new approach for the therapy of portal hypertension and chronic liver disease. Pigment epithelium-derived factor (PEDF) is a powerful endogenous angiogenesis inhibitor whose role in portal hypertension remains unknown. Therefore, we aimed
Carbon tetrachloride: genetic effects and other modes of action.
D McGregor et al.
Mutation research, 366(3), 181-195 (1996-12-01)
Mark A Barnes et al.
Journal of leukocyte biology, 97(1), 161-169 (2014-11-16)
Recruitment of peripheral monocytes to the liver is a key contributor to the response to injury. MIF can act as a chemokine and cytokine, regulating innate immune responses in many tissues and cell types. We hypothesized that MIF contributes to
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