方案
98%
SMILES字符串
O=C1NC(=O)c2nc[nH]c2N1
InChI
1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
InChI key
LRFVTYWOQMYALW-UHFFFAOYSA-N
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一般描述
Xanthine is a purine derivative. It has been reported to be formed during the metabolism of purine. Its presence in biological fluids is a marker of pathologic states, such as xanthinuria. Flavonoid nanostructured electrochemical sensor has been fabricated and employed for the voltammetric estimation of noradrenaline, acetaminophen, xanthine and caffeine, simultaneously.
应用
Xanthine may be employed in the superoxide dismutase (SOD) activity assay for the generation of superoxide radicals.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
A highly sensitive electrochemical sensor for simultaneous voltammetric determination of noradrenaline, acetaminophen, xanthine and caffeine based on a flavonoid nanostructured modified glassy carbon electrode.
Amiri-Aref M, et al.
Sensors and Actuators B, Chemical, 192, 634-641 (2014)
Roger Shek et al.
Biochemistry, 58(30), 3280-3292 (2019-07-10)
Guanine deaminase is a metabolic enzyme, found in all forms of life, which catalyzes the conversion of guanine to xanthine. Despite the availability of several crystal structures, the molecular determinants of substrate orientation and mechanism remain to be elucidated for
Avery G Frey et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(22), 8031-8036 (2014-05-21)
Although cells express hundreds of metalloenzymes, the mechanisms by which apoenzymes receive their metal cofactors are largely unknown. Poly(rC)-binding proteins PCBP1 and PCBP2 are multifunctional adaptor proteins that bind iron and deliver it to ferritin for storage or to prolyl
Sergey Dikalov et al.
Biochemical pharmacology, 76(5), 589-596 (2008-07-22)
Honokiol, a compound extracted from Magnolia officinalis, has antitumor and antiangiogenic properties in several tumor models in vivo. Among the downstream pathways inhibited by honokiol is nuclear factor kappa beta (NFkappabeta). A prime physiologic stimulus of NFkappabeta is reactive oxygen
S M Forget et al.
Organic & biomolecular chemistry, 13(3), 866-875 (2014-11-20)
Cps2L, a thymidylytransferase, is the first enzyme in Streptococcus pneumoniae L-rhamnose biosynthesis and an antibacterial target. We herein report the evaluation of six sugar phosphate analogues selected to further probe Cps2L substrate tolerance. A modified continuous spectrophotometric assay was employed
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