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Merck
CN

109541

黄嘌呤

98%

别名:

2,6-二羟基嘌呤

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关于此项目

经验公式(希尔记法):
C5H4N4O2
化学文摘社编号:
分子量:
152.11
EC Number:
200-718-6
UNSPSC Code:
41106305
PubChem Substance ID:
Beilstein/REAXYS Number:
8733
MDL number:
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assay

98%

SMILES string

O=C1NC(=O)c2nc[nH]c2N1

InChI

1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)

InChI key

LRFVTYWOQMYALW-UHFFFAOYSA-N

General description

Xanthine is a purine derivative. It has been reported to be formed during the metabolism of purine. Its presence in biological fluids is a marker of pathologic states, such as xanthinuria. Flavonoid nanostructured electrochemical sensor has been fabricated and employed for the voltammetric estimation of noradrenaline, acetaminophen, xanthine and caffeine, simultaneously.

Application

Xanthine may be employed in the superoxide dismutase (SOD) activity assay for the generation of superoxide radicals.


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存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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A highly sensitive electrochemical sensor for simultaneous voltammetric determination of noradrenaline, acetaminophen, xanthine and caffeine based on a flavonoid nanostructured modified glassy carbon electrode.
Amiri-Aref M, et al.
Sensors and Actuators B, Chemical, 192, 634-641 (2014)
Roger Shek et al.
Biochemistry, 58(30), 3280-3292 (2019-07-10)
Guanine deaminase is a metabolic enzyme, found in all forms of life, which catalyzes the conversion of guanine to xanthine. Despite the availability of several crystal structures, the molecular determinants of substrate orientation and mechanism remain to be elucidated for
Ken Okamoto et al.
Current pharmaceutical design, 19(14), 2606-2614 (2012-11-03)
Xanthine oxidoreductase (XOR), a complex flavoprotein, catalyzes the metabolic reactions leading from hypoxanthine to xanthine and from xanthine to urate, and both reactions take place at the molybdenum cofactor. The enzyme is a target of drugs for therapy of gout