10980
槟榔碱 氢溴酸盐
≥99.0% (NT)
别名:
1,2,5,6-四氢-1-甲基-3-吡啶羧酸甲酯 氢溴酸盐, 1-甲基-1,2,5,6-四氢-3-吡啶羧酸甲酯 氢溴酸盐, 1-甲基-1,2,5,6-四氢烟酸甲酯 氢溴酸盐, 槟榔碇甲酯 氢溴酸盐, 牛油菌素
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关于此项目
经验公式（希尔记法）:
C8H13NO2 · HBr
化学文摘社编号:
分子量:
236.11
EC Number:
206-087-3
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
3914826
MDL number:
InChI key
AXOJRQLKMVSHHZ-UHFFFAOYSA-N
InChI
1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H
SMILES string
Br[H].COC(=O)C1=CCCN(C)C1
assay
≥99.0% (NT)
mp
170-175 °C, 172-176 °C (lit.)
solubility
H2O: 0.1 g/mL, clear, colorless
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Other Notes
来源于棕榈种子的生物碱。有效用于人类研究
Hazard Classifications
Acute Tox. 4 Oral
signalword
Warning
hcodes
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
N Sitaram et al.
Science (New York, N.Y.), 201(4352), 274-276 (1978-07-21)
Arecholine (4 milligrams), a cholinergic agonist, and choline (10 grams), a precursor of acetylcholine, significantly enhanced serial learning in normal human subjects. The subjects received methscopolamine prior to both arecholine and placebo injections. Conversely, scopolamine (0.5 milligram), a cholinergic antagonist
Adrian A Franke et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 80, 241-246 (2015-03-24)
Betel nut chewing causes cancer in humans, including strong associations with head and neck cancer in Guam. In the search for biomarkers of betel chewing we sought to identify chemicals specific for the 3 most commonly consumed betel preparations in
Mafaz Ullah et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 43(10), 761-769 (2014-04-26)
Oral submucous fibrosis is a pre-malignant fibrotic condition caused by areca nut use and involves reduced mucosal vascularity. Arecoline is the principal areca nut alkaloid and is cytotoxic for epithelium and fibroblasts. Endothelial cell cycle arrest is reported on exposure
Tzer-Min Kuo et al.
Journal of agricultural and food chemistry, 63(24), 5787-5794 (2015-06-11)
The metabolites of environmental chemicals play key roles in carcinogenesis. Areca nut is strongly associated with the development of oral potentially malignant disorders (OPMD) or cancer. The main alkaloid in the areca nut is arecoline, which is highly cytotoxic and
Bing Li et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 969, 12-18 (2014-08-21)
A rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the determination of arecoline concentration in dog plasma. Plasma sample was prepared by protein precipitation using n-hexane (containing 1% isoamyl alcohol) with β-pinene as
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