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119792

罗汉松酸

Name: 罗汉松酸
Brand: ALDRICH

98%

别名:

(+)-Podocarpic acid, (1S)-1,2,3,4,4a,9,10,10a-Octahydro-6-hydroxy-1,4a-dimethyl-1-phenanthrenecarboxylic acid, (1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-6-hydroxy-1,4a-dimethyl-1-phenanthrenecarboxylic acid, Podocarpic acid (resin acid)

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关于此项目

经验公式（希尔记法）:

C₁₇H₂₂O₃

化学文摘社编号:

5947-49-9

分子量:

274.35

NACRES:

NA.22

PubChem Substance ID:

24847299

UNSPSC Code:

12352002

EC Number:

227-706-3

MDL number:

MFCD00074825

Assay:

98%

Form:

solid

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属性

Quality Level

100

assay

98%

form

solid

optical activity

[α]20/D +133°, c = 4 in ethanol

mp

193-196 °C (lit.)

functional group

carboxylic acid

SMILES string

[H][C@@]12CCc3ccc(O)cc3[C@@]1(C)CCC[C@]2(C)C(O)=O

InChI

1S/C17H22O3/c1-16-8-3-9-17(2,15(19)20)14(16)7-5-11-4-6-12(18)10-13(11)16/h4,6,10,14,18H,3,5,7-9H2,1-2H3,(H,19,20)/t14-,16-,17+/m1/s1

InChI key

VJILEYKNALCDDV-OIISXLGYSA-N

Gene Information

human ... TNF(7124)

说明

Application

(+)-Podocarpic acid as chiral template in the synthesis of aphidicolane, stemodane and stemarane diterpenoids: This article reviews the use of (+)-podocarpic acid in the synthesis of various diterpenoids, showcasing its utility in complex organic syntheses (La Bella et al., 2016).

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Inhibition of influenza virus hemagglutinin-mediated membrane fusion by a compound related to podocarpic acid.

K A Staschke et al.

Virology, 248(2), 264-274 (1998-08-29)

Entry of influenza virus into the host cell is dependent on the fusion of the viral envelope with the endosomal membrane and is mediated by a low-pH-induced change of the viral hemagglutinin (HA) to a conformation that is fusogenic. A

Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis.

Weiguo Liu et al.

Bioorganic & medicinal chemistry letters, 15(20), 4574-4578 (2005-08-30)

A series of podocarpic acid amides were identified as potent agonists for Liver X receptor alpha and beta subtypes, which are members of a nuclear hormone receptor superfamily that are involved in the regulation of a variety of metabolic pathways

Podocarpic acid as a source of an oestrogenic hormone.

C W BRANDT et al.

Nature, 161(4101), 892-892 (1948-06-05)

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全球贸易项目编号

货号	GTIN
119792-100MG	04061833278703
119792-1G	04061826661413