120693
α-甲基-DL-酪氨酸
98%
别名:
DL-2-甲基-3-(4-羟基苯基)丙氨酸, AMPT
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关于此项目
线性分子式:
4-(HO)C6H4CH2C(CH3)(NH2)CO2H
化学文摘社编号:
分子量:
195.22
EC Number:
211-523-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
2938704
MDL number:
InChI key
NHTGHBARYWONDQ-UHFFFAOYSA-N
InChI
1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)
SMILES string
CC(N)(Cc1ccc(O)cc1)C(O)=O
assay
98%
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
technique(s)
HPLC: suitable
color
white to off-white
mp
>300 °C (lit.)
application(s)
peptide synthesis
Gene Information
human ... TH(7054)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Joram D Mul et al.
PloS one, 8(3), e60214-e60214 (2013-04-05)
The orexigenic neuropeptide melanin-concentrating hormone (MCH), a product of Pmch, is an important mediator of energy homeostasis. Pmch-deficient rodents are lean and smaller, characterized by lower food intake, body-, and fat mass. Pmch is expressed in hypothalamic neurons that ultimately
Sunhoe Bang et al.
PLoS genetics, 7(3), e1001346-e1001346 (2011-04-02)
The ability to respond to environmental temperature variation is essential for survival in animals. Flies show robust temperature-preference behaviour (TPB) to find optimal temperatures. Recently, we have shown that Drosophila mushroom body (MB) functions as a center controlling TPB. However
Khoa D Nguyen et al.
Nature, 480(7375), 104-108 (2011-11-22)
All homeotherms use thermogenesis to maintain their core body temperature, ensuring that cellular functions and physiological processes can continue in cold environments. In the prevailing model of thermogenesis, when the hypothalamus senses cold temperatures it triggers sympathetic discharge, resulting in
Tong Liu et al.
PloS one, 4(2), e4574-e4574 (2009-02-25)
Dopamine is an important neuromodulator in animals and its roles in mammalian sexual behavior are extensively studied. Drosophila as a useful model system is widely used in many fields of biological studies. It has been reported that dopamine reduction can
Maria Xilouri et al.
PloS one, 4(5), e5515-e5515 (2009-05-14)
The mechanisms through which aberrant alpha-synuclein (ASYN) leads to neuronal death in Parkinson's disease (PD) are uncertain. In isolated liver lysosomes, mutant ASYNs impair Chaperone Mediated Autophagy (CMA), a targeted lysosomal degradation pathway; however, whether this occurs in a cellular
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