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123323

喹唑啉

Name: 喹唑啉
Brand: ALDRICH

99%

别名:

1,3-苯并二嗪, 苯并嘧啶

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关于此项目

经验公式（希尔记法）:

C₈H₆N₂

化学文摘社编号:

253-82-7

分子量:

130.15

EC Number:

205-965-3

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24847559

Beilstein/REAXYS Number:

109370

MDL number:

MFCD00006712

Assay:

99%

Form:

solid

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属性

Quality Level

100

assay

99%

form

solid

bp

243 °C (lit.)

mp

46-48 °C (lit.)

solubility

H₂O: freely soluble, organic solvents: soluble

SMILES string

c1ccc2ncncc2c1

InChI

1S/C8H6N2/c1-2-4-8-7(3-1)5-9-6-10-8/h1-6H

InChI key

JWVCLYRUEFBMGU-UHFFFAOYSA-N

说明

General description

Quinazolines has applications in medicinal chemistry due to their antibacterial, antifungal, anticonvulsant, anti-inflammatory and antitumor activities. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

Application

Quinazoline was used to study the electrochemical behaviour of quinazoline using modern polarographic and voltammetric methods.

Biochem/physiol Actions

Genotoxicity of quinazoline was established by bacterial SOS Chromotest (Escherichia Coli).

存储类别

11 - Combustible Solids

flash_point_f

222.8 °F - closed cup

flash_point_c

106 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

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Purine/purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors.

Kunal Nepali et al.

European journal of medicinal chemistry, 196, 112291-112291 (2020-04-24)

This study reports the design, synthesis and evaluation of a series of histone deacetylase (HDAC) inhibitors containing purine/purine isoster as a capping group and an N-(2-aminophenyl)-benzamide unit. In vitro cytotoxicity studies reveal that benzamide 14 suppressed the growth of triple-negative breast

An extended π-system and enhanced electronic delocalization on symmetric [Ru

Bruna Possato et al.

Dalton transactions (Cambridge, England : 2003), 46(24), 7926-7938 (2017-06-13)

We report on the investigation of a new series of symmetric trinuclear ruthenium complexes combined with azanaphthalene ligands: [Ru

Polarographic and voltammetric determination of quinazoline-the structural unit of anticancer drugs.

Hladikova J, et al.

Sensing in Electroanalysis, 3, 165-175 (2008)

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货号	GTIN
123323-5G	04061833544372
123323-1G	04061838722249