12348
(R)-1,4-苯并二噁烷-2-甲酸
≥97.0% (sum of enantiomers, GC)
别名:
(R)-2,3-二氢-1,4-苯并二噁英-2-羧酸
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关于此项目
经验公式（希尔记法）:
C9H8O4
化学文摘社编号:
分子量:
180.16
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5742837
InChI
1S/C9H8O4/c10-9(11)8-5-12-6-3-1-2-4-7(6)13-8/h1-4,8H,5H2,(H,10,11)/t8-/m1/s1
SMILES string
OC(=O)[C@H]1COc2ccccc2O1
InChI key
HMBHAQMOBKLWRX-MRVPVSSYSA-N
assay
≥97.0% (sum of enantiomers, GC)
form
solid
optical activity
[α]20/D +83±2°, c = 1.5% in chloroform
optical purity
enantiomeric ratio: ≥99.0:1.0
mp
96-99 °C
Application
(R)-1,4-Benzodioxane-2-carboxylic acid is a chiral synthon mostly used in the preparation of doxazosin mesylate, a drug treating benign prostatic hyperplasia.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Characterization of an Indole-3-Acetamide Hydrolase from Alcaligenes faecalis subsp. parafaecalis and Its Application in Efficient Preparation of Both Enantiomers of Chiral Building Block 2, 3-Dihydro-1, 4-Benzodioxin-2-Carboxylic Acid.
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