125504
环丙胺
98%
别名:
氨基环丙烷
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线性分子式:
C3H5NH2
化学文摘社编号:
分子量:
57.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-142-2
Beilstein/REAXYS Number:
741858
MDL number:
Assay:
98%
Form:
liquid
产品名称
环丙胺, 98%
InChI key
HTJDQJBWANPRPF-UHFFFAOYSA-N
InChI
1S/C3H7N/c4-3-1-2-3/h3H,1-2,4H2
SMILES string
NC1CC1
vapor pressure
4.67 psi ( 20 °C)
assay
98%
form
liquid
autoignition temp.
527 °F
refractive index
n20/D 1.420 (lit.)
bp
49-50 °C (lit.)
density
0.824 g/mL at 25 °C (lit.)
Quality Level
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Application
环丙胺 (CPA) 用于 N -\ [4-（4-氟）苯基-2-氨基噻唑-5-基] 嘧啶-2-基-烷基胺衍生物的合成 。已用于合成 Pt (CPA) 2 （ 双甲硫亚甲基丙二酸酯）和 Pt (CPA) 2 （双 乙基硫亚甲基丙二酸酯）配合物 。
Biochem/physiol Actions
环丙胺通过一种机制使细胞色素 P450 酶失活，该机制包括在氮气中先发生单电子氧化，然后环丙烷环断裂，导致酶的共价修饰 。它是 脱氮副球菌 中一种基于机制的喹啉甲胺脱氢酶抑制剂。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1B
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
33.8 °F - closed cup
flash_point_c
1 °C - closed cup
ppe
Faceshields, Gloves, Goggles
法规信息
危险化学品
此项目有
Dapeng Sun et al.
FEBS letters, 517(1-3), 172-174 (2002-06-14)
Cyclopropylamine is a mechanism-based inhibitor of the quinoprotein methylamine dehydrogenase (MADH) from Paracoccus denitrificans. The resulting inactivation is accompanied by the formation of a covalent cross-link between the alpha and beta subunits of MADH. The results of site-directed mutagenesis studies
Synthesis and Antifungal Activity of 5-[2-(Alkylamino) pyrimidin-4-yl]-4-phenylthiazol-2-cycloalkylamine Derivatives on Phytophthora capsici.
Nam Sw, et al.
J. Korean Chem. Soc., 54(3), 395-402 (2011)
Etienne Veignie et al.
Environmental pollution (Barking, Essex : 1987), 129(1), 1-4 (2004-01-30)
In order to study the enzymatic mechanisms involved in the successive steps of BaP degradation by a Deuteromycete fungus Fusarium solani, we developed an indirect approach by using inhibitors of enzymes. We used either specific inhibitors of peroxidases (i.e. salicylhydroxamic
Qin Sun et al.
Chemical research in toxicology, 21(3), 711-719 (2008-02-27)
Trovafloxacin (Trovan) is a fluoroquinolone antibiotic drug with a long half-life and broad-spectrum activity. Since its entry into the market in 1998, trovafloxacin has been associated with numerous cases of hepatotoxicity, which has limited its clinical usefulness. Trovafloxacin possesses two
David J Aitken et al.
Organic & biomolecular chemistry, 9(21), 7517-7524 (2011-09-23)
The Kulinkovich-de Meijere reaction between an unsaturated Grignard reagent and a chiral amide takes place with a high trans stereoselectivity and provides a convenient access to non-racemic trans cyclopropylamines. These compounds are transformed in four steps into the corresponding N-protected
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