蒸汽压
4.67 psi ( 20 °C)
质量水平
方案
98%
表单
liquid
自燃温度
527 °F
折射率
n20/D 1.420 (lit.)
沸点
49-50 °C (lit.)
密度
0.824 g/mL at 25 °C (lit.)
SMILES字符串
NC1CC1
InChI
1S/C3H7N/c4-3-1-2-3/h3H,1-2,4H2
InChI key
HTJDQJBWANPRPF-UHFFFAOYSA-N
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应用
环丙胺 (CPA) 用于 N -\ [4-（4-氟）苯基-2-氨基噻唑-5-基] 嘧啶-2-基-烷基胺衍生物的合成 。已用于合成 Pt (CPA) 2 （ 双甲硫亚甲基丙二酸酯）和 Pt (CPA) 2 （双 乙基硫亚甲基丙二酸酯）配合物 。
生化/生理作用
环丙胺通过一种机制使细胞色素 P450 酶失活，该机制包括在氮气中先发生单电子氧化，然后环丙烷环断裂，导致酶的共价修饰 。它是 脱氮副球菌 中一种基于机制的喹啉甲胺脱氢酶抑制剂。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1B
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
33.8 °F - closed cup
闪点(°C)
1 °C - closed cup
个人防护装备
Faceshields, Gloves, Goggles
法规信息
危险化学品
此项目有
Dapeng Sun et al.
FEBS letters, 517(1-3), 172-174 (2002-06-14)
Cyclopropylamine is a mechanism-based inhibitor of the quinoprotein methylamine dehydrogenase (MADH) from Paracoccus denitrificans. The resulting inactivation is accompanied by the formation of a covalent cross-link between the alpha and beta subunits of MADH. The results of site-directed mutagenesis studies
Synthesis and Antifungal Activity of 5-[2-(Alkylamino) pyrimidin-4-yl]-4-phenylthiazol-2-cycloalkylamine Derivatives on Phytophthora capsici.
Nam Sw, et al.
J. Korean Chem. Soc., 54(3), 395-402 (2011)
David J Aitken et al.
Organic & biomolecular chemistry, 9(21), 7517-7524 (2011-09-23)
The Kulinkovich-de Meijere reaction between an unsaturated Grignard reagent and a chiral amide takes place with a high trans stereoselectivity and provides a convenient access to non-racemic trans cyclopropylamines. These compounds are transformed in four steps into the corresponding N-protected
Etienne Veignie et al.
Environmental pollution (Barking, Essex : 1987), 129(1), 1-4 (2004-01-30)
In order to study the enzymatic mechanisms involved in the successive steps of BaP degradation by a Deuteromycete fungus Fusarium solani, we developed an indirect approach by using inhibitors of enzymes. We used either specific inhibitors of peroxidases (i.e. salicylhydroxamic
Fluorinated phenylcyclopropylamines as inhibitors of monoamine oxidases.
Thomas C Rosen et al.
Chembiochem : a European journal of chemical biology, 5(8), 1033-1043 (2004-08-10)
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