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Merck
CN

125504

环丙胺

98%

别名:

氨基环丙烷

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关于此项目

线性分子式:
C3H5NH2
化学文摘社编号:
分子量:
57.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-142-2
Beilstein/REAXYS Number:
741858
MDL number:
Assay:
98%
Form:
liquid
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vapor pressure

4.67 psi ( 20 °C)

Quality Level

assay

98%

form

liquid

autoignition temp.

527 °F

refractive index

n20/D 1.420 (lit.)

bp

49-50 °C (lit.)

density

0.824 g/mL at 25 °C (lit.)

SMILES string

NC1CC1

InChI

1S/C3H7N/c4-3-1-2-3/h3H,1-2,4H2

InChI key

HTJDQJBWANPRPF-UHFFFAOYSA-N

Application

环丙胺 (CPA) 用于 N -\ [4-(4-氟)苯基-2-氨基噻唑-5-基] 嘧啶-2-基-烷基胺衍生物的合成 。已用于合成 Pt (CPA) 2 甲硫亚甲基丙二酸酯)和 Pt (CPA) 2 乙基硫亚甲基丙二酸酯)配合物 。

Biochem/physiol Actions

环丙胺通过一种机制使细胞色素 P450 酶失活,该机制包括在氮气中先发生单电子氧化,然后环丙烷环断裂,导致酶的共价修饰 。它是 脱氮副球菌 中一种基于机制的喹啉甲胺脱氢酶抑制剂。


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signalword

Danger

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

33.8 °F - closed cup

flash_point_c

1 °C - closed cup

ppe

Faceshields, Gloves, Goggles

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

法规信息

危险化学品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis and Antifungal Activity of 5-[2-(Alkylamino) pyrimidin-4-yl]-4-phenylthiazol-2-cycloalkylamine Derivatives on Phytophthora capsici.
Nam Sw, et al.
J. Korean Chem. Soc., 54(3), 395-402 (2011)
Dapeng Sun et al.
FEBS letters, 517(1-3), 172-174 (2002-06-14)
Cyclopropylamine is a mechanism-based inhibitor of the quinoprotein methylamine dehydrogenase (MADH) from Paracoccus denitrificans. The resulting inactivation is accompanied by the formation of a covalent cross-link between the alpha and beta subunits of MADH. The results of site-directed mutagenesis studies
Jo-Yanne Le Berre et al.
PloS one, 12(12), e0190341-e0190341 (2017-12-28)
Little is known about the responses of plant roots to filamentous pathogens, particularly to oomycetes. To assess the molecular dialog established between the host and the pathogen during early stages of infection, we investigated the overall changes in gene expression



全球贸易项目编号

货号GTIN
125504-25G04061838723628
125504-10G04061838723611